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Anti-EPOR Monoclonal Antibody-AF488
Anti-EPOR Monoclonal Antibody-AF488
Anti-EPOR Monoclonal Antibody-AF488 is a Biotin-conjugated rabbit antibody targeting EPOR. Anti-EPOR Monoclonal Antibody-AF488 can be used in ELISA, FACS, IF.
Catalog No. TMAZ-0026A4
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Anti-EPOR Monoclonal Antibody-AF488
Catalog No. TMAZ-0026A4Alias Erythropoietin receptor
Anti-EPOR Monoclonal Antibody-AF488 is a Biotin-conjugated rabbit antibody targeting EPOR. Anti-EPOR Monoclonal Antibody-AF488 can be used in ELISA, FACS, IF.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 μg | Inquiry | 12 days | |
| 50 μg | Inquiry | 12 days | |
| 100 μg | Inquiry | 12 days |
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Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-EPOR Monoclonal Antibody-AF488 is a Biotin-conjugated rabbit antibody targeting EPOR. Anti-EPOR Monoclonal Antibody-AF488 can be used in ELISA, FACS, IF. |
| Alias | Erythropoietin receptor |
| Ig Type | Rabbit monoclonal IgG |
| Reactivity | Human |
| Verified Activity | Flow cytometry analysis of EPOR overexpressed 371F cells with TMAZ-0026A4, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line). |
| Application | ELISA, FACS, IF |
| Recommended Dose | 0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted |
| Construction | This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of EPOR protein. |
| Purification | Protein A Affinity Purified |
| Appearance | Liquid |
| Formulation | 0.22 μm filtered solution in 20 mM HEPES7.4, 150 mM NaCl, 50% glycerol and 0.03% proclin. |
| Purity | > 95% as determined by SDS-PAGE. |
| Research Background | Receptor for erythropoietin, which mediates erythropoietin-induced erythroblast proliferation and differentiation (PubMed: 10388848, PubMed: 2163695, PubMed: 2163696, PubMed: 8662939, PubMed: 9774108). Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade (By similarity). In some cell types, can also activate STAT1 and STAT3 (PubMed: 11756159). May also activate the LYN tyrosine kinase (By similarity)|Acts as a dominant-negative receptor of EPOR-mediated signaling |
| Conjucates | AF488 |
| Others Formats | Biotin/APC/PE/AF555/AF647 |
| Antibody Types Available | 2 |
| Immunogen | EPOR |
| Antigen Species | Human |
| Gene ID | 2057 |
| Uniprot ID | |
| Biology Area | Immunology Research |
| Molecular Weight | 150 kDa |
Stability & Storage
| Stability & Storage | For unconjugated and biotin antibody, store at -20°C or -80°C for long term. Avoid repeated freeze-thaw cycles. For APC/PE/AF647/AF555/AF488 conjugated antibody, store at 4°C, do not freeze. |
| Transport | For unconjugated and biotin antibody, shipping with dry ice. For APC/PE/AF647/AF555/AF488 conjugated antibody, shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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