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Anti-EPOR Monoclonal Antibody-AF555

Catalog No. TMAZ-0026A5
Alias Erythropoietin receptor

Anti-EPOR Monoclonal Antibody-AF555 is a Biotin-conjugated rabbit antibody targeting EPOR. Anti-EPOR Monoclonal Antibody-AF555 can be used in ELISA, FACS, IF.

Anti-EPOR Monoclonal Antibody-AF555

Anti-EPOR Monoclonal Antibody-AF555

Catalog No. TMAZ-0026A5Alias Erythropoietin receptor
Anti-EPOR Monoclonal Antibody-AF555 is a Biotin-conjugated rabbit antibody targeting EPOR. Anti-EPOR Monoclonal Antibody-AF555 can be used in ELISA, FACS, IF.
Pack SizePriceAvailabilityQuantity
25 μg$57012 days
50 μg$94512 days
100 μg$1,41512 days
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Product Introduction

Bioactivity
Description
Anti-EPOR Monoclonal Antibody-AF555 is a Biotin-conjugated rabbit antibody targeting EPOR. Anti-EPOR Monoclonal Antibody-AF555 can be used in ELISA, FACS, IF.
AliasErythropoietin receptor
Ig Type
Rabbit monoclonal IgG
Reactivity
Human
Verified Activity
Flow cytometry analysis of EPOR overexpressed 371F cells with TMAZ-0026A5, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line).
Application
ELISA, FACS, IF
Recommended Dose
0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationSecreted
ConstructionThis antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of EPOR protein.
PurificationProtein A Affinity Purified
AppearanceLiquid
Formulation0.22 μm filtered solution in 20 mM HEPES7.4, 150 mM NaCl, 50% glycerol and 0.03% proclin.
Purity> 95% as determined by SDS-PAGE.
Research BackgroundReceptor for erythropoietin, which mediates erythropoietin-induced erythroblast proliferation and differentiation (PubMed: 10388848, PubMed: 2163695, PubMed: 2163696, PubMed: 8662939, PubMed: 9774108). Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade (By similarity). In some cell types, can also activate STAT1 and STAT3 (PubMed: 11756159). May also activate the LYN tyrosine kinase (By similarity)|Acts as a dominant-negative receptor of EPOR-mediated signaling
Related Conjugates and Formulations
Conjucates
AF555
Others Formats
Biotin/APC/PE/AF488/AF647
Antibody Types Available
2
Antigen Details
Immunogen
EPOR
Antigen Species
Human
Gene ID
2057
Uniprot ID
Biology Area
Immunology Research
Chemical Properties
Molecular Weight150 kDa
Stability & Storage
Stability & StorageFor unconjugated and biotin antibody, store at -20°C or -80°C for long term. Avoid repeated freeze-thaw cycles. For APC/PE/AF647/AF555/AF488 conjugated antibody, store at 4°C, do not freeze.
TransportFor unconjugated and biotin antibody, shipping with dry ice. For APC/PE/AF647/AF555/AF488 conjugated antibody, shipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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