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Anti-F2 Monoclonal Antibody-AF488
Catalog No. TMAZ-0378A4
Alias Prothrombin, Coagulation factor II
Anti-F2 Monoclonal Antibody-AF488 is a biotin-conjugated rabbit antibody targeting F2. Anti-F2 Monoclonal Antibody-AF488 can be used in ELISA, FACS.
Anti-F2 Monoclonal Antibody-AF488
Anti-F2 Monoclonal Antibody-AF488
Catalog No. TMAZ-0378A4Alias Prothrombin, Coagulation factor II
Anti-F2 Monoclonal Antibody-AF488 is a biotin-conjugated rabbit antibody targeting F2. Anti-F2 Monoclonal Antibody-AF488 can be used in ELISA, FACS.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 μg | $570 | 12 days | |
| 50 μg | $945 | 12 days | |
| 100 μg | $1,415 | 12 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-F2 Monoclonal Antibody-AF488 is a biotin-conjugated rabbit antibody targeting F2. Anti-F2 Monoclonal Antibody-AF488 can be used in ELISA, FACS. |
| Alias | Prothrombin, Coagulation factor II |
| Ig Type | Rabbit monoclonal IgG |
| Reactivity | Human |
| Verified Activity | Flow cytometry analysis of F2 overexpressed 448F cells with TMAZ-0378A4, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line). |
| Application | ELISA, FACS |
| Recommended Dose | 0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted |
| Construction | This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of F2 protein. |
| Purification | Protein A Affinity Purified |
| Appearance | Liquid |
| Purity | > 95% as determined by SDS-PAGE. |
| Research Background | Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing. Thrombin triggers the production of pro-inflammatory cytokines, such as MCP-1/CCL2 and IL8/CXCL8, in endothelial cells (PubMed:30568593, PubMed:9780208) |
| Others Formats | Biotin/APC/PE/AF555/AF647 |
| Antibody Types Available | 1 |
| Immunogen | F2 |
| Antigen Species | Human |
| Gene ID | 2147 |
| Uniprot ID | |
| Biology Area | Drug Target |
| Molecular Weight | 150 kDa |
Stability & Storage
| Stability & Storage | For unconjugated and biotin antibody, store at -20°C or -80°C for long term. Avoid repeated freeze-thaw cycles. For APC/PE/AF647/AF555/AF488 conjugated antibody, store at 4°C, do not freeze. |
| Transport | For unconjugated and biotin antibody, shipping with dry ice. For APC/PE/AF647/AF555/AF488 conjugated antibody, shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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