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Anti-KITLG Monoclonal Antibody-PE

Catalog No. TMAZ-0211P
Alias Stem cell factor, Mast cell growth factor, Kit ligand, c-Kit ligand

Anti-KITLG Monoclonal Antibody-PE is a Biotin-conjugated rabbit antibody targeting KITLG. Anti-KITLG Monoclonal Antibody-PE can be used in ELISA, FACS, IF.

Anti-KITLG Monoclonal Antibody-PE

Anti-KITLG Monoclonal Antibody-PE

Catalog No. TMAZ-0211PAlias Stem cell factor, Mast cell growth factor, Kit ligand, c-Kit ligand
Anti-KITLG Monoclonal Antibody-PE is a Biotin-conjugated rabbit antibody targeting KITLG. Anti-KITLG Monoclonal Antibody-PE can be used in ELISA, FACS, IF.
Pack SizePriceAvailabilityQuantity
25 μg$23012 days
50 μg$38512 days
100 μg$57512 days
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Product Introduction

Bioactivity
Description
Anti-KITLG Monoclonal Antibody-PE is a Biotin-conjugated rabbit antibody targeting KITLG. Anti-KITLG Monoclonal Antibody-PE can be used in ELISA, FACS, IF.
AliasStem cell factor, Mast cell growth factor, Kit ligand, c-Kit ligand
Ig Type
Rabbit monoclonal IgG
Reactivity
Human
Verified Activity
Flow cytometry analysis of KITLG overexpressed 427F cells with TMAZ-0211P, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line).
Application
ELISA, FACS, IF
Recommended Dose
0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationSingle-pass type I membrane
ConstructionThis antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of KITLG protein.
PurificationProtein A Affinity Purified
AppearanceLiquid
Formulation0.22 μm filtered solution in 20 mM HEPES7.4, 150 mM NaCl, 50% glycerol and 0.03% proclin.
Purity> 95% as determined by SDS-PAGE.
Research BackgroundLigand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Promotes phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1. KITLG/SCF and KIT also transmit signals via GRB2 and activation of RAS, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. KITLG/SCF and KIT promote activation of STAT family members STAT1, STAT3 and STAT5. KITLG/SCF and KIT promote activation of PLCG1, leading to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate. KITLG/SCF acts synergistically with other cytokines, probably interleukins
Related Conjugates and Formulations
Conjucates
PE
Others Formats
Biotin/APC/AF488/AF555/AF647
Antibody Types Available
2
Antigen Details
Immunogen
KITLG
Antigen Species
Human
Gene ID
4254
Uniprot ID
Biology Area
Cytokines
Chemical Properties
Molecular Weight150 kDa
Stability & Storage
Stability & StorageFor unconjugated and biotin antibody, store at -20°C or -80°C for long term. Avoid repeated freeze-thaw cycles. For APC/PE/AF647/AF555/AF488 conjugated antibody, store at 4°C, do not freeze.
TransportFor unconjugated and biotin antibody, shipping with dry ice. For APC/PE/AF647/AF555/AF488 conjugated antibody, shipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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