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Anti-MICB Monoclonal Antibody-AF488
Anti-MICB Monoclonal Antibody-AF488
Anti-MICB Monoclonal Antibody-AF488 is a Biotin-conjugated rabbit antibody targeting MICB. Anti-MICB Monoclonal Antibody-AF488 can be used in ELISA, FACS, IF.
Catalog No. TMAZ-0189A4
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Anti-MICB Monoclonal Antibody-AF488
Catalog No. TMAZ-0189A4Alias MHC class I polypeptide-related sequence B
Anti-MICB Monoclonal Antibody-AF488 is a Biotin-conjugated rabbit antibody targeting MICB. Anti-MICB Monoclonal Antibody-AF488 can be used in ELISA, FACS, IF.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 μg | Inquiry | 12 days | |
| 50 μg | Inquiry | 12 days | |
| 100 μg | Inquiry | 12 days |
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Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-MICB Monoclonal Antibody-AF488 is a Biotin-conjugated rabbit antibody targeting MICB. Anti-MICB Monoclonal Antibody-AF488 can be used in ELISA, FACS, IF. |
| Alias | MHC class I polypeptide-related sequence B |
| Ig Type | Rabbit monoclonal IgG |
| Reactivity | Human |
| Verified Activity | Flow cytometry analysis of MICB overexpressed 326F cells with TMAZ-0189A4, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line). |
| Application | ELISA, FACS, IF |
| Recommended Dose | 0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Single-pass type I membrane |
| Construction | This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of MICB protein. |
| Purification | Protein A Affinity Purified |
| Appearance | Liquid |
| Formulation | 0.22 μm filtered solution in 20 mM HEPES7.4, 150 mM NaCl, 50% glycerol and 0.03% proclin. |
| Purity | > 95% as determined by SDS-PAGE. |
| Research Background | Widely expressed membrane-bound protein which acts as a ligand to stimulate an activating receptor KLRK1/NKG2D, expressed on the surface of essentially all human natural killer (NK), gammadelta T and CD8+ alphabeta T-cells (PubMed: 11777960, PubMed: 11491531). Up-regulated in stressed conditions, such as viral and bacterial infections or DNA damage response, serves as signal of cellular stress, and engagement of KLRK1/NKG2D by MICA triggers NK-cells resulting in a range of immune effector functions, such as cytotoxicity and cytokine production |
| Conjucates | AF488 |
| Others Formats | Biotin/APC/PE/AF555/AF647 |
| Antibody Types Available | 2 |
| Immunogen | MICB |
| Antigen Species | Human |
| Gene ID | 4277 |
| Uniprot ID | |
| Biology Area | Drug Target |
| Molecular Weight | 150 kDa |
Stability & Storage
| Stability & Storage | For unconjugated and biotin antibody, store at -20°C or -80°C for long term. Avoid repeated freeze-thaw cycles. For APC/PE/AF647/AF555/AF488 conjugated antibody, store at 4°C, do not freeze. |
| Transport | For unconjugated and biotin antibody, shipping with dry ice. For APC/PE/AF647/AF555/AF488 conjugated antibody, shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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