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Anti-NECTIN2 Monoclonal Antibody-AF488
Anti-NECTIN2 Monoclonal Antibody-AF488
Anti-NECTIN2 Monoclonal Antibody-AF488 is a Biotin-conjugated rabbit antibody targeting NECTIN2. Anti-NECTIN2 Monoclonal Antibody-AF488 can be used in ELISA, FACS.
Catalog No. TMAZ-0230A4
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Anti-NECTIN2 Monoclonal Antibody-AF488
Catalog No. TMAZ-0230A4Alias Poliovirus receptor-related protein 2, Nectin-2, Nectin cell adhesion molecule 2, Herpes virus entry mediator B
Anti-NECTIN2 Monoclonal Antibody-AF488 is a Biotin-conjugated rabbit antibody targeting NECTIN2. Anti-NECTIN2 Monoclonal Antibody-AF488 can be used in ELISA, FACS.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 μg | $395 | 12 days | |
| 50 μg | $655 | 12 days | |
| 100 μg | $985 | 12 days |
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Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-NECTIN2 Monoclonal Antibody-AF488 is a Biotin-conjugated rabbit antibody targeting NECTIN2. Anti-NECTIN2 Monoclonal Antibody-AF488 can be used in ELISA, FACS. |
| Alias | Poliovirus receptor-related protein 2, Nectin-2, Nectin cell adhesion molecule 2, Herpes virus entry mediator B |
| Ig Type | Rabbit monoclonal IgG |
| Reactivity | Human |
| Verified Activity | Flow cytometry analysis of NECTIN2 overexpressed 439F cells with TMAZ-0230A4, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line). |
| Application | ELISA, FACS |
| Recommended Dose | 0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted |
| Construction | This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of NECTIN2 protein. |
| Purification | Protein A Affinity Purified |
| Appearance | Liquid |
| Formulation | 0.22 μm filtered solution in 20 mM HEPES7.4, 150 mM NaCl, 50% glycerol and 0.03% proclin. |
| Purity | > 95% as determined by SDS-PAGE. |
| Research Background | Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG, inhibits T-cell proliferation. These interactions are competitive (PubMed: 26755705). Probable cell adhesion protein (PubMed: 9657005)|(Microbial infection) Acts as a receptor for herpes simplex virus 1 (HHV-1) mutant Rid1, herpes simplex virus 1 (HHV-2) and pseudorabies virus (PRV) |
| Conjucates | AF488 |
| Others Formats | Biotin/APC/PE/AF555/AF647 |
| Antibody Types Available | 1 |
| Immunogen | NECTIN2 |
| Antigen Species | Human |
| Gene ID | 5819 |
| Uniprot ID | |
| Biology Area | Other Functions |
| Molecular Weight | 150 kDa |
Stability & Storage
| Stability & Storage | For unconjugated and biotin antibody, store at -20°C or -80°C for long term. Avoid repeated freeze-thaw cycles. For APC/PE/AF647/AF555/AF488 conjugated antibody, store at 4°C, do not freeze. |
| Transport | For unconjugated and biotin antibody, shipping with dry ice. For APC/PE/AF647/AF555/AF488 conjugated antibody, shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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