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Anti-NECTIN2 Monoclonal Antibody-AF647 is a Biotin-conjugated rabbit antibody targeting NECTIN2. Anti-NECTIN2 Monoclonal Antibody-AF647 can be used in ELISA, FACS.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 μg | $395 | 12 days | |
50 μg | $655 | 12 days | |
100 μg | $985 | 12 days |
Description | Anti-NECTIN2 Monoclonal Antibody-AF647 is a Biotin-conjugated rabbit antibody targeting NECTIN2. Anti-NECTIN2 Monoclonal Antibody-AF647 can be used in ELISA, FACS. |
Alias | Poliovirus receptor-related protein 2, Nectin-2, Nectin cell adhesion molecule 2, Herpes virus entry mediator B |
Ig Type | Rabbit monoclonal IgG |
Reactivity | Human |
Verified Activity | Flow cytometry analysis of NECTIN2 overexpressed 439F cells with TMAZ-0230A6, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line). |
Application | ELISA, FACS |
Recommended Dose | 0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Subcellular Localization | Secreted |
Construction | This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of NECTIN2 protein. |
Purification | Protein A Affinity Purified |
Appearance | Liquid |
Formulation | 0.22 μm filtered solution in 20 mM HEPES7.4, 150 mM NaCl, 50% glycerol and 0.03% proclin. |
Purity | > 95% as determined by SDS-PAGE. |
Research Background | Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG, inhibits T-cell proliferation. These interactions are competitive (PubMed: 26755705). Probable cell adhesion protein (PubMed: 9657005)|(Microbial infection) Acts as a receptor for herpes simplex virus 1 (HHV-1) mutant Rid1, herpes simplex virus 1 (HHV-2) and pseudorabies virus (PRV) |
Conjucates | AF647 |
Others Formats | Biotin/APC/PE/AF488/AF555 |
Antibody Types Available | 1 |
Immunogen | NECTIN2 |
Antigen Species | Human |
Gene ID | 5819 |
Uniprot ID | |
Biology Area | Other Functions |
Molecular Weight | 150 kDa |
Stability & Storage | For unconjugated and biotin antibody, store at -20°C or -80°C for long term. Avoid repeated freeze-thaw cycles. For APC/PE/AF647/AF555/AF488 conjugated antibody, store at 4°C, do not freeze. |
Transport | For unconjugated and biotin antibody, shipping with dry ice. For APC/PE/AF647/AF555/AF488 conjugated antibody, shipping with blue ice. |
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