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Anti-TNFRSF1B Monoclonal Antibody-AF488 is a Biotin-conjugated rabbit antibody targeting TNFRSF1B. Anti-TNFRSF1B Monoclonal Antibody-AF488 can be used in ELISA, FACS, IF.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 μg | $380 | 12 days | |
50 μg | $630 | 12 days | |
100 μg | $945 | 12 days |
Description | Anti-TNFRSF1B Monoclonal Antibody-AF488 is a Biotin-conjugated rabbit antibody targeting TNFRSF1B. Anti-TNFRSF1B Monoclonal Antibody-AF488 can be used in ELISA, FACS, IF. |
Alias | Tumor necrosis factor receptor type II, Tumor necrosis factor receptor superfamily member 1B, Tumor necrosis factor receptor 2, p80 TNF-alpha receptor, p75 |
Ig Type | Rabbit monoclonal IgG |
Reactivity | Human |
Verified Activity | Flow cytometry analysis of TNFRSF1B overexpressed 293F cells with TMAZ-0045A4BI, which was counjucated with SA-PE (red). The WT 293F control is black line. |
Application | ELISA, FACS, IF |
Recommended Dose | 0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Subcellular Localization | Single-pass type I membrane |
Construction | This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of TNFRSF1B protein. |
Purification | Protein A Affinity Purified |
Appearance | Liquid |
Formulation | 0.22 μm filtered solution in 20 mM HEPES7.4, 150 mM NaCl, 50% glycerol and 0.03% proclin. |
Purity | > 95% as determined by SDS-PAGE. |
Research Background | Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity |
Conjucates | AF488 |
Others Formats | Biotin/APC/PE/AF555/AF647 |
Antibody Types Available | 1 |
Immunogen | TNFRSF1B |
Antigen Species | Human |
Gene ID | 7133 |
Uniprot ID | |
Biology Area | Immunology Research |
Molecular Weight | 150 kDa |
Stability & Storage | For unconjugated and biotin antibody, store at -20°C or -80°C for long term. Avoid repeated freeze-thaw cycles. For APC/PE/AF647/AF555/AF488 conjugated antibody, store at 4°C, do not freeze. |
Transport | For unconjugated and biotin antibody, shipping with dry ice. For APC/PE/AF647/AF555/AF488 conjugated antibody, shipping with blue ice. |
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