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Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $1,330 | 6-8 weeks | |
50 mg | $1,730 | 6-8 weeks | |
100 mg | $2,500 | 6-8 weeks |
Description | c-di-AMP (Cyclic diadenylate) is a STING agonist that binds to the transmembrane protein STING, thereby activating the TBK3-IRF3 signaling pathway. |
In vitro | c-di-AMP signaling is a central factor in many Gram-positive bacteria regulating cell wall synthesis, potassium ion channels, DNA repair, and biofilm formation. c-di-AMP is also essential for cell growth, survival, and virulence of several well-known human pathogenic bacteria [1]. c-di-AMP combines with model antigens, such as OVA or β-Gal, acts as a potent mucosal adjuvant stimulating both humoral and cellular responses [4]. |
Alias | Cyclic diadenylate, Cyclic-di-AMP |
Molecular Weight | 658.41 |
Formula | C20H24N10O12P2 |
Cas No. | 54447-84-6 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||
Solubility Information | H2O: 5.5 mg/mL (8.35 mM), Sonication is recommended. | |||||||||||||||
Solution Preparation Table | ||||||||||||||||
H2O
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