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COX-2-IN-43
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Catalog No. T86084Cas No. 1023524-40-4
COX-2-IN-43 (Compound MYM4) functions as a selective COX-2 inhibitor, exhibiting IC50 values of 0.983 μM for COX-1 and 0.247 μM for COX-2. It effectively inhibits cancer cell proliferation and colonization and also induces apoptosis [1].
COX-2-IN-43
😃Good
Catalog No. T86084Cas No. 1023524-40-4
COX-2-IN-43 (Compound MYM4) functions as a selective COX-2 inhibitor, exhibiting IC50 values of 0.983 μM for COX-1 and 0.247 μM for COX-2. It effectively inhibits cancer cell proliferation and colonization and also induces apoptosis [1].
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 10 mg | Inquiry | 10-14 weeks | |
| 50 mg | Inquiry | 10-14 weeks |
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Product Introduction
Bioactivity
Chemical Properties
| Description | COX-2-IN-43 (Compound MYM4) functions as a selective COX-2 inhibitor, exhibiting IC50 values of 0.983 μM for COX-1 and 0.247 μM for COX-2. It effectively inhibits cancer cell proliferation and colonization and also induces apoptosis [1]. |
| Targets&IC50 | COX-1:14.86 μM |
| In vitro | COX-2-IN-43 inhibits the proliferation of CaCo-2, Hep3B, and HeLa cancer cells, with IC50 values of 10.22, 4.84, and 1.57 μM, respectively [1]. |
| Molecular Weight | 431.19 |
| Formula | C18H11Cl2F3N2O3 |
| Cas No. | 1023524-40-4 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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