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DSPE-PEG-CH2COOH (MW 5000) is a polyethylene glycol (PEG)-based proteolysis targeting chimera (PROTAC) linker. It serves as an essential component in the synthesis of PROTACs, enabling the targeted degradation of specific proteins[1].
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | DSPE-PEG-CH2COOH (MW 5000) is a polyethylene glycol (PEG)-based proteolysis targeting chimera (PROTAC) linker. It serves as an essential component in the synthesis of PROTACs, enabling the targeted degradation of specific proteins[1]. |
In vitro | PROTACs, comprising two ligands joined by a linker—one for E3 ubiquitin ligase and the other for the target protein—utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1]. |
Relative Density. | no data available |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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