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DSPE-PEG(2000)-Azide

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Catalog No. T201885Cas No. 1938081-39-0
Alias azide-DSPE-PEG2000, 1,2-DSPE-PEG(2000)-azide, 1,2-Distearoyl-sn-glycero-3-Phosphoethanolamine-N-[azido(Polyethylene Glycol)-2000], 1,2-Distearoyl-sn-glycero-3-PE-Polyethylene Glycol-2000-azide

DSPE-PEG(2000)-azide is a PEGylated derivative based on 1,2-distearoyl-sn-glycero-3-phosphoethanolamine (1,2-DSPE). This compound is utilized for attaching vascular cell adhesion molecule-1 (VCAM-1) antibodies to vesicles that encapsulate fingolimod, aiming to target the delivery of fingolimod to inflammatory vessels in mouse models simulating post-ischemic neuroinflammation. Additionally, DSPE-PEG(2000)-azide is employed to link fibrinogen mimetic peptides (FMP) to the surface of synthetic platelets used in treating uncontrollable bleeding caused by liver damage in mouse models.

DSPE-PEG(2000)-Azide

DSPE-PEG(2000)-Azide

😃Good
Catalog No. T201885Alias azide-DSPE-PEG2000, 1,2-DSPE-PEG(2000)-azide, 1,2-Distearoyl-sn-glycero-3-Phosphoethanolamine-N-[azido(Polyethylene Glycol)-2000], 1,2-Distearoyl-sn-glycero-3-PE-Polyethylene Glycol-2000-azideCas No. 1938081-39-0
DSPE-PEG(2000)-azide is a PEGylated derivative based on 1,2-distearoyl-sn-glycero-3-phosphoethanolamine (1,2-DSPE). This compound is utilized for attaching vascular cell adhesion molecule-1 (VCAM-1) antibodies to vesicles that encapsulate fingolimod, aiming to target the delivery of fingolimod to inflammatory vessels in mouse models simulating post-ischemic neuroinflammation. Additionally, DSPE-PEG(2000)-azide is employed to link fibrinogen mimetic peptides (FMP) to the surface of synthetic platelets used in treating uncontrollable bleeding caused by liver damage in mouse models.
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Product Introduction

Bioactivity
Description
DSPE-PEG(2000)-azide is a PEGylated derivative based on 1,2-distearoyl-sn-glycero-3-phosphoethanolamine (1,2-DSPE). This compound is utilized for attaching vascular cell adhesion molecule-1 (VCAM-1) antibodies to vesicles that encapsulate fingolimod, aiming to target the delivery of fingolimod to inflammatory vessels in mouse models simulating post-ischemic neuroinflammation. Additionally, DSPE-PEG(2000)-azide is employed to link fibrinogen mimetic peptides (FMP) to the surface of synthetic platelets used in treating uncontrollable bleeding caused by liver damage in mouse models.
Aliasazide-DSPE-PEG2000, 1,2-DSPE-PEG(2000)-azide, 1,2-Distearoyl-sn-glycero-3-Phosphoethanolamine-N-[azido(Polyethylene Glycol)-2000], 1,2-Distearoyl-sn-glycero-3-PE-Polyethylene Glycol-2000-azide
Chemical Properties
Formula(C2H4O)nC44H85N4O10P
Cas No.1938081-39-0
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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