Name: Edogesterone
Brand: TargetMol
SKU: T202823
Rating: 4.5 (1 reviews)

Edogesterone

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Catalog No. T202823Alias PH-218, PH 218, Edogestrone, 9014UFK50CCas No. 809-01-8

Edogesterone (PH-218) is a steroid compound characterized by its progestogenic and antiandrogenic properties.

Pack Size	Price	Availability	Quantity
10 mg	Inquiry	10-14 weeks
50 mg	Inquiry	10-14 weeks

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QWhat’s ED50?

AEffective dose 50 (ED50）refers to the dose of a drug that produces a specific effect in 50% of the population that has been administered that dose.

QWhat’s IC50?

AHalf-maximal inhibitory concentration (IC50) refers to the concentration of the inhibitor which is required to inhibit a given biological or biochemical function by half.

QWhat’s Kd?

ADissociation consent (Kd) reflects the affinity of a compound for its target. In some cases, it can be equivalent to Ki.

QHow to recommend specific or broad-spectrum inhibitors for a target? What is the difference between specificity and nonspecificity?

AInhibitors can be classified into two types based on specificity: broad-spectrum (pan) and selective inhibitors. Pan inhibitors are inhibitors of a particular target that have inhibitory effects on all subtypes or members of the entire family. Selective inhibitors have particularly high inhibitory rates or specific inhibitory effects on a subtype of a protein kinase or a member of a family of proteins. The evaluation of the inhibitory efficiency of an inhibitor generally relies on the IC50 value, with lower IC50 values indicating higher inhibitory efficiency. We recommend considering the above characteristics comprehensively when selecting inhibitors, and you can also contact our technical team for recommendations on relevant inhibitors.

QWhat’s pIC50?

ApIC50 is the negative log of the IC50 value when converted to molar.That is, pIC50=-log(IC50).

Product Introduction

Bioactivity

Description	Edogesterone (PH-218) is a steroid compound characterized by its progestogenic and antiandrogenic properties.
Alias	PH-218, PH 218, Edogestrone, 9014UFK50C

Chemical Properties

Molecular Weight	430.58
Formula	C₂₆H₃₈O₅
Cas No.	809-01-8

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.