Shopping Cart
- Remove All
![TargetMol](https://newstatic.targetmol.com/error/oops.webp)
Your shopping cart is currently empty
Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $2,720 | Inquiry | |
50 mg | $3,580 | Inquiry | |
100 mg | $4,900 | Inquiry |
Description | Elomotecan (BN 80927 free base), a camptothecin analog from the homocamptothecin family (hCPT), serves as a potent inhibitor of topoisomerases I and II. It effectively reduces the proliferation of various tumor cells more significantly than other reference anticancer drugs targeting the same topoisomerases [1].This compound is unstable in powder form and other related salt forms are recommended. |
In vitro | WEHI-539 induces noticeable PARP cleavage in Ovcar-4 (5 μM in Ovcar-4.) and Ovsaho (1 μM in Ovsaho) cells. WEHI-539 augments Carboplatin induced caspase 3/7 activity, PARP cleavage, and annexin V labeling.[2] |
Alias | BN 80927 free base |
Molecular Weight | 522.04 |
Formula | C29H32ClN3O4 |
Cas No. | 220998-10-7 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.