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FX12 acts as a selective inhibitor and degrader of the RNF5 E3 ubiquitin ligase. It directly binds to RNF5, inhibiting its E3 activity in vitro and facilitates the proteasomal degradation of RNF5 in cells through ERAD.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
10 mg | Inquiry | 10-14 weeks | |
50 mg | Inquiry | 10-14 weeks |
Description | FX12 acts as a selective inhibitor and degrader of the RNF5 E3 ubiquitin ligase. It directly binds to RNF5, inhibiting its E3 activity in vitro and facilitates the proteasomal degradation of RNF5 in cells through ERAD. |
Molecular Weight | 224.23 |
Formula | C10H8O4S |
Cas No. | 1807639-36-6 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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