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Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $1,520 | 6-8 weeks | |
50 mg | $1,980 | 6-8 weeks | |
100 mg | $2,500 | 6-8 weeks |
Description | GlcN-6-P Synthase-IN-1 (Compound 4d) is a potent inhibitor of Glucosamine-6-phosphate (GlcN-6-P) synthase, with an IC50 of 3.47 μM. This compound demonstrates remarkable antimicrobial activity and exhibits excellent penetration in the central nervous system. Additionally, GlcN-6-P Synthase-IN-1 is capable of inhibiting cytochrome P450, specifically the CYP3A4 isoform [1]. |
In vitro | GlcN-6-P Synthase-IN-1 (Compound 4d) displays antimicrobial properties, as evidenced by its minimum inhibitory concentration (MIC) values. These values are 1 ± 0.15 μg/mL against S. aureus, 0.5 ± 0.15 μg/mL against B. subtilis, and 4 ± 0.33 μg/mL for both C. albicans and A. oryzae, indicating its effective inhibition of these microorganisms [1]. |
Molecular Weight | 391.49 |
Formula | C20H21N7S |
Cas No. | 2447602-44-8 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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