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GPR120 Agonist 4

Name: GPR120 Agonist 4
Brand: TargetMol
SKU: T86518
Price: 41 USD
Availability: InStock
Rating: 4.5 (1 reviews)

GPR120 Agonist 4 (example 1), a GPR120 agonist, exhibits EC50 values of 1 μM for β-arrestin A and 0.35 μM for Calcium A. This compound is utilized in research related to type II diabetes mellitus [1].

Catalog No. T86518Cas No. 1628641-89-3

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GPR120 Agonist 4

Catalog No. T86518Cas No. 1628641-89-3

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Pack Size	Price	Availability	Quantity
10 mg	Inquiry	10-14 weeks
50 mg	Inquiry	10-14 weeks

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Product Introduction

Bioactivity

Description	GPR120 Agonist 4 (example 1), a GPR120 agonist, exhibits EC50 values of 1 μM for β-arrestin A and 0.35 μM for Calcium A. This compound is utilized in research related to type II diabetes mellitus [1].
Targets&IC50	GPR120:1 μM (EC 50 )
In vitro	GPR120 Agonist 4 (example 1), at concentrations of 0.012-25 μM over 90 minutes, activates GPR120 in CHO-K1 GPR120 β-arrestin cells through the recruitment of β-arrestin [1]. Additionally, GPR120 Agonist 4 (0.012-25 μM, 90 min) facilitates calcium ion release in HEK293 cells overexpressing human GPR120, confirming its effectiveness in activating GPR120 [1].
In vivo	GPR120 Agonist 4 (example 1), administered intraperitoneally at doses of 0.2/0.3/1/3/10 mg/kg for 15/30/45/60/90 minutes, promotes a dose-dependent reduction in glucose levels in a high-fat diet mouse model [1]. Furthermore, at doses of 1/3/10 mg/kg for the same time intervals, it inhibits the rise in glucose levels in a fasting mouse model in a dose-dependent manner [1].

Chemical Properties

Molecular Weight	459.79
Formula	C₂₁H₁₅ClF₅NO₃
Cas No.	1628641-89-3

Storage & Solubility Information

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Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

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