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Hit 14

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Catalog No. T88707Cas No. 440338-68-1

Hit 14, a CXCR4 (C-X-C chemokine receptor type 4) inhibitor, demonstrates an IC50 of 254 nM. It inhibits migration and invasion of MDA-MB-231 cells and suppresses Akt phosphorylation, exhibiting anti-inflammatory activity. Furthermore, Hit 14 improves ear swelling and damage in a mouse model.

Hit 14

Hit 14

😃Good
Catalog No. T88707Cas No. 440338-68-1
Hit 14, a CXCR4 (C-X-C chemokine receptor type 4) inhibitor, demonstrates an IC50 of 254 nM. It inhibits migration and invasion of MDA-MB-231 cells and suppresses Akt phosphorylation, exhibiting anti-inflammatory activity. Furthermore, Hit 14 improves ear swelling and damage in a mouse model.
Pack SizePriceAvailabilityQuantity
10 mgInquiry10-14 weeks
50 mgInquiry10-14 weeks
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Product Introduction

Bioactivity
Description
Hit 14, a CXCR4 (C-X-C chemokine receptor type 4) inhibitor, demonstrates an IC50 of 254 nM. It inhibits migration and invasion of MDA-MB-231 cells and suppresses Akt phosphorylation, exhibiting anti-inflammatory activity. Furthermore, Hit 14 improves ear swelling and damage in a mouse model.
Targets&IC50
12G5 mAb-CXCR4:254 nM
Chemical Properties
Molecular Weight496.6
FormulaC22H28N2O7S2
Cas No.440338-68-1
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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