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HSD17B13-IN-14 (Compound 4) acts as a potent inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), achieving an IC 50 of ≤ 1 μM for leukotriene B3 and ≤ 0.1 μM for estradiol. This compound is utilized in studying various conditions, including liver diseases, metabolic disorders, and cardiovascular diseases like NAFLD or NASH, as well as drug-induced liver injury (DILI) [1].
Pack Size | Price | Availability | Quantity |
---|---|---|---|
10 mg | Inquiry | 10-14 weeks | |
50 mg | Inquiry | 10-14 weeks |
Description | HSD17B13-IN-14 (Compound 4) acts as a potent inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), achieving an IC 50 of ≤ 1 μM for leukotriene B3 and ≤ 0.1 μM for estradiol. This compound is utilized in studying various conditions, including liver diseases, metabolic disorders, and cardiovascular diseases like NAFLD or NASH, as well as drug-induced liver injury (DILI) [1]. |
Molecular Weight | 425.89 |
Formula | C21H16ClN3O3S |
Cas No. | 2758802-05-8 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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