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L-Azidohomoalanine

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Catalog No. T15693Cas No. 120042-14-0

L-Azidohomoalanine, an alkyl chain-derived PROTAC linker, is utilized in the synthesis of PROTACs[1].

L-Azidohomoalanine

L-Azidohomoalanine

😃Good
Catalog No. T15693Cas No. 120042-14-0
L-Azidohomoalanine, an alkyl chain-derived PROTAC linker, is utilized in the synthesis of PROTACs[1].
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Product Introduction

Bioactivity
Description
L-Azidohomoalanine, an alkyl chain-derived PROTAC linker, is utilized in the synthesis of PROTACs[1].
In vitro
PROTACs comprise two distinct ligands joined by a linker, one targeting an E3 ubiquitin ligase and the other the desired protein. They utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Chemical Properties
Molecular Weight144.13
FormulaC4H8N4O2
Cas No.120042-14-0
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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Keywords

L AzidohomoalanineLAzidohomoalanineL-Azidohomoalanine
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