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LY2023-001

Catalog No. T89605Cas No. 327031-30-1

LY2023-001 is an effective inhibitor of G2019SLRRK2, with an IC50 value of 12.9 nM. It forms stable hydrogen bonds with Glu1948 and Ala1950 in the G2019SLRRK2 protein.

LY2023-001

LY2023-001

Catalog No. T89605Cas No. 327031-30-1
LY2023-001 is an effective inhibitor of G2019SLRRK2, with an IC50 value of 12.9 nM. It forms stable hydrogen bonds with Glu1948 and Ala1950 in the G2019SLRRK2 protein.
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10 mgInquiry10-14 weeks
50 mgInquiry10-14 weeks
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Product Introduction

Bioactivity
Description
LY2023-001 is an effective inhibitor of G2019SLRRK2, with an IC50 value of 12.9 nM. It forms stable hydrogen bonds with Glu1948 and Ala1950 in the G2019SLRRK2 protein.
Chemical Properties
Molecular Weight378.39
FormulaC19H18N6O3
Cas No.327031-30-1
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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