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Maridebart cafraglutide

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Catalog No. T9901A-169Cas No. 2887445-76-1
Alias AMG 133

Maridebart cafraglutide, an antibody-peptide conjugate, serves as a GLP-1 receptor agonist and a GIP receptor antagonist. It effectively reduces body weight and enhances metabolic markers in male obese mice and cynomolgus monkeys, showing promise for obesity research.

Maridebart cafraglutide

Maridebart cafraglutide

😃Good
Catalog No. T9901A-169Alias AMG 133Cas No. 2887445-76-1
Maridebart cafraglutide, an antibody-peptide conjugate, serves as a GLP-1 receptor agonist and a GIP receptor antagonist. It effectively reduces body weight and enhances metabolic markers in male obese mice and cynomolgus monkeys, showing promise for obesity research.
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Product Introduction

Bioactivity
Description
Maridebart cafraglutide, an antibody-peptide conjugate, serves as a GLP-1 receptor agonist and a GIP receptor antagonist. It effectively reduces body weight and enhances metabolic markers in male obese mice and cynomolgus monkeys, showing promise for obesity research.
AliasAMG 133
Chemical Properties
Cas No.2887445-76-1
Storage & Solubility Information
Storagestore at -20°C | Shipping with blue ice.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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