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MK-8527

Name: MK-8527
Brand: TargetMol
SKU: T86907
Rating: 4.5 (1 reviews)

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Catalog No. T86907Cas No. 1810869-23-8

MK-8527, an HIV inhibitor and nucleoside reverse transcriptase translocation inhibitor (NRTTI), exhibits a similar inhibitory mechanism to ISL [1].

MK-8527

😃Good

Catalog No. T86907Cas No. 1810869-23-8

MK-8527, an HIV inhibitor and nucleoside reverse transcriptase translocation inhibitor (NRTTI), exhibits a similar inhibitory mechanism to ISL [1].

Pack Size	Price	Availability
1 mg	$987	10-14 weeks
5 mg	$1,980	10-14 weeks
10 mg	$2,770	10-14 weeks
25 mg	$3,970	10-14 weeks
50 mg	$5,550	10-14 weeks
100 mg	$7,490	10-14 weeks

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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity

Description

MK-8527, an HIV inhibitor and nucleoside reverse transcriptase translocation inhibitor (NRTTI), exhibits a similar inhibitory mechanism to ISL [1].

Chemical Properties

Molecular Weight	308.72
Formula	C₁₃H₁₃ClN₄O₃
Cas No.	1810869-23-8

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc