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Pack Size | Price | Availability | Quantity |
---|---|---|---|
2 mg | $36 | 5 days | |
5 mg | $55 | 5 days |
Description | NH-bis(PEG4-acid) is a PEG-based linker used in PROTACs to connect two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells. |
In vitro | PROTACs, comprising two distinct ligands linked together—one targeting an E3 ubiquitin ligase and the other the target protein—utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1]. |
Molecular Weight | 513.58 |
Formula | C22H43NO12 |
Cas No. | 2055041-59-1 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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