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OICR-8268 is a reversible ligand for the DCAF1 WDR domain, exhibiting a Kd of 38 nM, and facilitates the development of DCAF1-based PROTACs [1].
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10 mg | Inquiry | Inquiry | |
50 mg | Inquiry | Inquiry |
Description | OICR-8268 is a reversible ligand for the DCAF1 WDR domain, exhibiting a Kd of 38 nM, and facilitates the development of DCAF1-based PROTACs [1]. |
In vitro | OICR-8268 binds to the DCAF1 WDR domain within NCI-H460 cells, exhibiting an EC 50 of 10.5 μM [1]. |
Molecular Weight | 439.24 |
Formula | C19H14Cl2F2N4O2 |
Cas No. | 3000549-26-5 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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