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Quinacrine mustard hydrochloride

Quinacrine mustard hydrochloride
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Quinacrine mustard hydrochloride

Catalog No. T37031Cas No. 4213-45-0
Quinacrine mustard hydrochloride is a fluorescent dye and polycyclic aromatic agent that acts as a mutagen to induce mutants in bacteria.Quinacrine mustard hydrochloride selectively binds to adenine-thymine (AT) base pairs, but not to guanine-cytosine (GC). Quinacrine mustard (hydrochloride) selectively binds to adenine-thymine (AT) base pairs rather than to guanine-cytosine (GC) base pairs, inducing cell cycle arrest at G2/M. Quinacrine mustard (hydrochloride) has been used to label chromosomes for karyotyping by autoradiography.
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Pack SizePriceAvailabilityQuantity
5 mg$14835 days
10 mg$25835 days
25 mg$57835 days
50 mg$1,07835 days
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Product Introduction

Bioactivity
Description
Quinacrine mustard hydrochloride is a fluorescent dye and polycyclic aromatic agent that acts as a mutagen to induce mutants in bacteria.Quinacrine mustard hydrochloride selectively binds to adenine-thymine (AT) base pairs, but not to guanine-cytosine (GC). Quinacrine mustard (hydrochloride) selectively binds to adenine-thymine (AT) base pairs rather than to guanine-cytosine (GC) base pairs, inducing cell cycle arrest at G2/M. Quinacrine mustard (hydrochloride) has been used to label chromosomes for karyotyping by autoradiography.
In vitro
Quinacrine mustard hydrochloride (0.2 μM; 4h) induced cell cycle arrest at G2+M-phase with the accumulation of cells in this compartment by 50% in HL-60 cells.[1]
Quinacrine mustard hydrochloride (5 μg/ml) can be used for the DNA strain of plant, animal, or human chromosomes.[2]
Quinacrine mustard hydrochloride (28 μM) increases the number of mutants that appeared after exposure to bacteria.[3]
AliasQuinacrine mustard HCl
Chemical Properties
Molecular Weight505.31
FormulaC23H29Cl4N3O
Cas No.4213-45-0
Storage & Solubility Information
Storagestore at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
Chloroform: Soluble
H2O: Soluble

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