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Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $148 | 35 days | |
10 mg | $258 | 35 days | |
25 mg | $578 | 35 days | |
50 mg | $1,078 | 35 days |
Description | Quinacrine mustard hydrochloride is a fluorescent dye and polycyclic aromatic agent that acts as a mutagen to induce mutants in bacteria.Quinacrine mustard hydrochloride selectively binds to adenine-thymine (AT) base pairs, but not to guanine-cytosine (GC). Quinacrine mustard (hydrochloride) selectively binds to adenine-thymine (AT) base pairs rather than to guanine-cytosine (GC) base pairs, inducing cell cycle arrest at G2/M. Quinacrine mustard (hydrochloride) has been used to label chromosomes for karyotyping by autoradiography. |
In vitro | Quinacrine mustard hydrochloride (0.2 μM; 4h) induced cell cycle arrest at G2+M-phase with the accumulation of cells in this compartment by 50% in HL-60 cells.[1] Quinacrine mustard hydrochloride (5 μg/ml) can be used for the DNA strain of plant, animal, or human chromosomes.[2] Quinacrine mustard hydrochloride (28 μM) increases the number of mutants that appeared after exposure to bacteria.[3] |
Alias | Quinacrine mustard HCl |
Molecular Weight | 505.31 |
Formula | C23H29Cl4N3O |
Cas No. | 4213-45-0 |
Storage | store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Solubility Information | Chloroform: Soluble H2O: Soluble |
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