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Serclutamab talirine

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Catalog No. T9901A-026Cas No. 2140174-56-5
Alias ABBV-321

Serclutamab talirine (ABBV-321), an EGFR-targeted antibody-drug conjugate (ADC), comprises the AM-1-ABT-806 antibody, which targets activated EGFR, and a pyrrolobenzodiazepine (PBD) dimer. This compound displays potent antitumor activity [1].

Serclutamab talirine

Serclutamab talirine

😃Good
Catalog No. T9901A-026Alias ABBV-321Cas No. 2140174-56-5
Serclutamab talirine (ABBV-321), an EGFR-targeted antibody-drug conjugate (ADC), comprises the AM-1-ABT-806 antibody, which targets activated EGFR, and a pyrrolobenzodiazepine (PBD) dimer. This compound displays potent antitumor activity [1].
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Bioactivity
Description
Serclutamab talirine (ABBV-321), an EGFR-targeted antibody-drug conjugate (ADC), comprises the AM-1-ABT-806 antibody, which targets activated EGFR, and a pyrrolobenzodiazepine (PBD) dimer. This compound displays potent antitumor activity [1].
AliasABBV-321
Chemical Properties
Cas No.2140174-56-5
Storage & Solubility Information
StorageShipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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