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SR1555 hydrochloride
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Catalog No. T89635Cas No. 2309312-90-9
SR1555 hydrochloride is the hydrochloride salt form of SR1555. It acts as an inverse agonist for the retinoic acid receptor-related orphan receptor γ (RORγ), with an IC50 of 1 μM. This compound inhibits the development and function of pro-inflammatory TH17 cells while increasing the frequency of anti-inflammatory regulatory T (Treg) cells. SR1555 hydrochloride is utilized in research related to autoimmune diseases.
SR1555 hydrochloride
😃Good
Catalog No. T89635Cas No. 2309312-90-9
SR1555 hydrochloride is the hydrochloride salt form of SR1555. It acts as an inverse agonist for the retinoic acid receptor-related orphan receptor γ (RORγ), with an IC50 of 1 μM. This compound inhibits the development and function of pro-inflammatory TH17 cells while increasing the frequency of anti-inflammatory regulatory T (Treg) cells. SR1555 hydrochloride is utilized in research related to autoimmune diseases.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 10 mg | Inquiry | 10-14 weeks | |
| 50 mg | Inquiry | 10-14 weeks |
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Product Introduction
Bioactivity
Chemical Properties
| Description | SR1555 hydrochloride is the hydrochloride salt form of SR1555. It acts as an inverse agonist for the retinoic acid receptor-related orphan receptor γ (RORγ), with an IC50 of 1 μM. This compound inhibits the development and function of pro-inflammatory TH17 cells while increasing the frequency of anti-inflammatory regulatory T (Treg) cells. SR1555 hydrochloride is utilized in research related to autoimmune diseases. |
| Molecular Weight | 496.87 |
| Formula | C22H23ClF6N2O2 |
| Cas No. | 2309312-90-9 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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