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Tenofovir-C3-O-C12-trimethylsilylacetylene ammonium

Catalog No. T40238Cas No. 2611373-74-9
Alias Tenofovir-C3-O-C12-trimethylsilylacetylene ammonium

Tenofovir-C3-O-C12-trimethylsilylacetylene (ammonium) exhibits a prolonged half-life (t1/2) compared to tenofovir in human liver microsomes, demonstrates potent in vitro anti-HIV activity, and improves in vivo pharmacokinetic properties.

Tenofovir-C3-O-C12-trimethylsilylacetylene ammonium

Tenofovir-C3-O-C12-trimethylsilylacetylene ammonium

Catalog No. T40238Alias Tenofovir-C3-O-C12-trimethylsilylacetylene ammoniumCas No. 2611373-74-9
Tenofovir-C3-O-C12-trimethylsilylacetylene (ammonium) exhibits a prolonged half-life (t1/2) compared to tenofovir in human liver microsomes, demonstrates potent in vitro anti-HIV activity, and improves in vivo pharmacokinetic properties.
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Product Introduction

Bioactivity
Description
Tenofovir-C3-O-C12-trimethylsilylacetylene (ammonium) exhibits a prolonged half-life (t1/2) compared to tenofovir in human liver microsomes, demonstrates potent in vitro anti-HIV activity, and improves in vivo pharmacokinetic properties.
AliasTenofovir-C3-O-C12-trimethylsilylacetylene ammonium
Chemical Properties
Molecular Weight626.855
FormulaC29H55N6O5PSi
Cas No.2611373-74-9
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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