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Teprasiran

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Catalog No. T38616Cas No. 1231737-88-4
Alias QPI-1002

Teprasiran (QPI-1002) is an RNA-based compound that transiently suppresses p53-dependent apoptosis, a process involved in the development of acute kidney injury (AKI).

Teprasiran

Teprasiran

😃Good
Catalog No. T38616Alias QPI-1002Cas No. 1231737-88-4
Teprasiran (QPI-1002) is an RNA-based compound that transiently suppresses p53-dependent apoptosis, a process involved in the development of acute kidney injury (AKI).
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Product Introduction

Bioactivity
Description
Teprasiran (QPI-1002) is an RNA-based compound that transiently suppresses p53-dependent apoptosis, a process involved in the development of acute kidney injury (AKI).
In vitro
Teprasiran is a synthetic, chemically stabilized small interfering RNA (siRNA) that induces RNA interference to transiently suppress p53 expression for approximately 48 to 72 hours[1].
AliasQPI-1002
Chemical Properties
Cas No.1231737-88-4
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

QPI 1002QPI1002Teprasiran
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