keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
TNF-α antagonist is an exocyclic peptide that mimics the critical TNF-α recognition loop on TNF receptor I complex and, thus, prevents ligand interaction with the receptor. By blocking the TNF receptor ligand contact site, this peptide interferes with both activating receptor activator of NF-κB (RANK) and TNF-α's recruitment and activation of osteoclasts. TNF-α antagonist has been used to block bone resorption in the study of systemic bone loss in rheumatoid arthritis and inflammatory bone destruction.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
500 μg | 35 days | $ 296.00 | |
1 mg | 35 days | $ 575.00 | |
5 mg | 35 days | $ 2,400.00 |
Description | TNF-α antagonist is an exocyclic peptide that mimics the critical TNF-α recognition loop on TNF receptor I complex and, thus, prevents ligand interaction with the receptor. By blocking the TNF receptor ligand contact site, this peptide interferes with both activating receptor activator of NF-κB (RANK) and TNF-α's recruitment and activation of osteoclasts. TNF-α antagonist has been used to block bone resorption in the study of systemic bone loss in rheumatoid arthritis and inflammatory bone destruction. |
Molecular Weight | 1226.39 |
Formula | C58H71N11O15S2 |
CAS No. | 199999-60-5 |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO:PBS(pH7.2) (1:1): 0.5 mg/mL
DMSO: 5 mg/mL
You can also refer to dose conversion for different animals. More
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TNF-α Antagonist 199999-60-5 TNFα Antagonist TNF-a Antagonist TNF α Antagonist TNF-alpha Antagonist inhibitor inhibit