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Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $1,520 | 10-14 weeks | |
50 mg | $1,980 | 10-14 weeks | |
100 mg | $2,500 | 10-14 weeks |
Description | Tubulin inhibitor 16 is a potent tubulin inhibitor with antiproliferative activity. Tubulin inhibitor 16 exhibits cytotoxicity in HepG2 cells [1]. |
In vitro | Tubulin inhibitor 16 (compound 2) (0-25 μM, 24 h followed by a 72 h compound-free incubation period) exhibits antiproliferative activity with IC 50 s of 1.43, 0.19, 2.33, 0.58, 0.83, 0.20, >25 μM for MCF7, MDA-MB-231, HepG2, SNU423, A549, HCT116, THLE-3 cells [1]. Cell Proliferation Assay [1] Cell Line: MCF7, MDA-MB-231, HepG2, SNU423, A549, HCT116 cells Concentration: 0-50 μM Incubation Time: 96 h Result: Exhibited antiproliferative activity with IC 50 s of 0.75, 0.17, 3.12, 0.41, 0.37, 0.22 μM for MCF7, MDA-MB-231, HepG2, SNU423, A549, HCT116 cells, respectively. Cell Cytotoxicity Assay [1] Cell Line: HepG2 cells Concentration: 0.5, 1 μM Incubation Time: 14 days Result: No colonies were evident when cells were treated with 0.5 or 1 μM. |
Molecular Weight | 269.27 |
Formula | C16H12FNO2 |
Cas No. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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