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UK4b is a highly selective inhibitor of microsomal prostaglandin E2 synthase-1 (mPGES-1), exhibiting anti-inflammatory and analgesic properties, and capable of inhibiting the growth of abdominal aortic aneurysms in mice [1].
Pack Size | Price | Availability | Quantity |
---|---|---|---|
10 mg | Inquiry | 10-14 weeks | |
50 mg | Inquiry | 10-14 weeks |
Description | UK4b is a highly selective inhibitor of microsomal prostaglandin E2 synthase-1 (mPGES-1), exhibiting anti-inflammatory and analgesic properties, and capable of inhibiting the growth of abdominal aortic aneurysms in mice [1]. |
In vivo | UK4b, administered subcutaneously at 10-20 mg/kg twice daily for 22 consecutive days, can inhibit the further growth of abdominal aortic aneurysm (AAA) in an ApoE−/− angiotensin (Ang) II (1000 ng/kg/min; infusion, for 28 consecutive days) induced AAA mouse model [1]. |
Molecular Weight | 404.89 |
Formula | C21H25ClN2O4 |
Cas No. | 2171000-87-4 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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