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Ulenistamab (PBP1510) is a first-in-class humanized IgG1 monoclonal antibody targeting the pancreatic adenocarcinoma upregulated factor (PAUF), and is used in pancreatic cancer (PC) research [1].
Pack Size | Price | Availability | Quantity |
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1 mg | Inquiry | Backorder | |
5 mg | Inquiry | Backorder |
Description | Ulenistamab (PBP1510) is a first-in-class humanized IgG1 monoclonal antibody targeting the pancreatic adenocarcinoma upregulated factor (PAUF), and is used in pancreatic cancer (PC) research [1]. |
In vitro | Ulenistamab (PBP1510) inhibits the proliferation of pancreatic cancer cell lines (CFPAC-1 and BxPC-3). Concurrently, there is a significant reduction in the migration and invasion of these cell lines [1]. |
In vivo | The pharmacokinetic (PK) profiles and immunogenicity of Ulenistamab (PBP1510) (up to 20 mg/kg) were examined in a single-dose study involving 6 monkeys. Systemic exposure in the monkey study was observed to increase in a dose-proportional manner at both low and high doses [1]. |
Alias | PBP1510 |
Cas No. | 2415259-90-2 |
Storage | store at -20°C | Shipping with blue ice. |
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