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YX968

Name: YX968
Brand: TargetMol
SKU: T88929
Rating: 4.5 (1 reviews)

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Catalog No. T88929Cas No. 2742732-92-7

YX968 is an effective selective dual degrader of HDAC3/8, with DC50 values of 1.7 and 6.8 nM respectively. It exerts its anti-tumor activity by inducing cell apoptosis (apoptosis).

YX968

😃Good

Catalog No. T88929Cas No. 2742732-92-7

YX968 is an effective selective dual degrader of HDAC3/8, with DC50 values of 1.7 and 6.8 nM respectively. It exerts its anti-tumor activity by inducing cell apoptosis (apoptosis).

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Product Introduction

Bioactivity

Description	YX968 is an effective selective dual degrader of HDAC3/8, with DC50 values of 1.7 and 6.8 nM respectively. It exerts its anti-tumor activity by inducing cell apoptosis (apoptosis).
Targets&IC50	HDAC8:6.8 nM (DC50), HDAC3:1.7 nM (DC50)
In vitro	YX968 (1 μM, 24 h) induces apoptosis by blocking cell cycle at the G1 phase.

Chemical Properties

Molecular Weight	831.12
Formula	C₄₅H₆₆N₈O₅S
Cas No.	2742732-92-7

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

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Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

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