Shopping Cart

Remove All
Your shopping cart is currently empty

Z57346765

Name: Z57346765
Brand: TargetMol
SKU: T87659
Rating: 4.5 (1 reviews)

😃Good

Catalog No. T87659Cas No. 1016340-64-9

Alias Z 57346765

Z57346765 is a specific PGK1(Phosphoglycerate kinase 1) inhibitor that inhibits PGK1-dependent cell proliferation by decreasing the metabolic enzyme activity of PGK1 during glycolysis. In the clinical phase, Z57346765 had a dose-dependent inhibitory effect on locally advanced renal clear cell carcinoma (KIRC) by inducing changes in the expression of genes related to cell metabolism, DNA replication, and the cell cycle.

Z57346765

😃Good

Catalog No. T87659Alias Z 57346765Cas No. 1016340-64-9

Pack Size	Price	Availability
1 mg	$48	10-14 weeks
5 mg	$113	10-14 weeks
10 mg	$168	10-14 weeks
25 mg	$339	10-14 weeks
50 mg	$513	10-14 weeks
100 mg	$768	10-14 weeks
200 mg	$1,050	10-14 weeks

Bulk & Custom

Add to Cart

Questions

Resource Download

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity

Description

Alias

Z 57346765

Chemical Properties

Molecular Weight	294.35
Formula	C₁₇H₁₈N₄O
Cas No.	1016340-64-9

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 80 mg/mL (271.79 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.3973 mL	16.9866 mL	33.9732 mL	169.8658 mL
5 mM	0.6795 mL	3.3973 mL	6.7946 mL	33.9732 mL
10 mM	0.3397 mL	1.6987 mL	3.3973 mL	16.9866 mL
20 mM	0.1699 mL	0.8493 mL	1.6987 mL	8.4933 mL
50 mM	0.0679 mL	0.3397 mL	0.6795 mL	3.3973 mL
100 mM	0.0340 mL	0.1699 mL	0.3397 mL	1.6987 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc