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3CLpro/3C-like Protease Protein, SARS-CoV-2, Recombinant
Catalog No. TMPJ-01449
The viral main proteinase (M pro , also called 3CL pro ), which controls the activities of the coronavirus replication complex. It functions as a cysteine protease engaging in the proteolytic cleavage of the viral precursor polyprotein to a series of functional proteins required for coronavirus replication and is considered as an appealing target for designing anti-SARS agents. 3CLpro/3C-like Protease Protein, SARS-CoV-2, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 30 kDa and the accession number is P0DTC1.
3CLpro/3C-like Protease Protein, SARS-CoV-2, Recombinant
Catalog No. TMPJ-01449
The viral main proteinase (M pro , also called 3CL pro ), which controls the activities of the coronavirus replication complex. It functions as a cysteine protease engaging in the proteolytic cleavage of the viral precursor polyprotein to a series of functional proteins required for coronavirus replication and is considered as an appealing target for designing anti-SARS agents. 3CLpro/3C-like Protease Protein, SARS-CoV-2, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 30 kDa and the accession number is P0DTC1.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 10 μg | $231 | 7-10 days | |
| 50 μg | $511 | 7-10 days | |
| 500 μg | $3,720 | 7-10 days | |
| 1 mg | $5,590 | 7-10 days |
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Product Information
| Biological Activity | Measured by its ability to cleave a fluorogenic peptide substrate, Dabcyl-KTSAVLQSGFRKME-Edans (Synthetic). The specific activity is 136.6pmol/min/μg. (Regularly tested) |
| Description | The viral main proteinase (M pro , also called 3CL pro ), which controls the activities of the coronavirus replication complex. It functions as a cysteine protease engaging in the proteolytic cleavage of the viral precursor polyprotein to a series of functional proteins required for coronavirus replication and is considered as an appealing target for designing anti-SARS agents. 3CLpro/3C-like Protease Protein, SARS-CoV-2, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 30 kDa and the accession number is P0DTC1. |
| Species | SARS-CoV-2 |
| Expression System | E. coli |
| Tag | Tag Free |
| Accession Number | P0DTC1 |
| Synonyms | M Proteinase,3C-like Proteinase,3CL Proteinase |
| Amino Acid | Ser3264-Gln3569 |
| Construction | Ser3264-Gln3569 |
| Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
| Molecular Weight | 30 kDa (reducing condition) |
| Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Formulation | Supplied as a 0.2 μm filtered solution of 50 mM Tris-HCl, 1 mM EDTA, pH7.3. |
| Stability & Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | Shipping with blue ice. |
| Research Background | The viral main proteinase (M pro , also called 3CL pro ), which controls the activities of the coronavirus replication complex. It functions as a cysteine protease engaging in the proteolytic cleavage of the viral precursor polyprotein to a series of functional proteins required for coronavirus replication and is considered as an appealing target for designing anti-SARS agents. |
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