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ADAM8/CD156a Protein, Rhesus, Recombinant (His)

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ADAM8/CD156a Protein, Rhesus, Recombinant (His)

Catalog No. TMPY-03877

ADAM8/CD156a Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 53.6 kDa and the accession number is XP_002805919.1.

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Pack Size	Price	Availability	Quantity
20 μg	$297	7-10 days
100 μg	$700	7-10 days

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Biological Description

Biological Information	Measured by its ability to cleave a fluorogenic peptide substrate Mca-PLAQAV-Dpa-RSSSR-NH2. The specific activity is > 0.5 pmols/min/μg.
Description	ADAM8/CD156a Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 53.6 kDa and the accession number is XP_002805919.1.
Species	Rhesus
Expression System	HEK293 Cells
Tag	C-His
Accession Number	XP_002805919.1
Synonyms	ADAM metallopeptidase domain 8
Construction	The rhesus ADAM8 (XP_002805919.1) (Met1-Pro497) was expressed with a polyhistidine tag at the C-terminus.
Protein Purity	> 85 % as determined by SDS-PAGE
Molecular Weight	53.6 kDa (predicted)
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Supplied as sterile 12. 5 mM Tris, 5 mM CaCl2, 75 mM NaCl, 50% glycerol.
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage	It is recommended to store the product under sterile conditions at -20°C to -80°C. Samples are stable for up to 12 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
Research Background	ADAM8, also known as CD156, is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. ADAM8 is possiblely involved in extravasation of leukocytes As a metalloprotease, ADAM8 also may be involved in cell adhesion during neurodegeneration, and it is thought to be a target for allergic respiratory diseases, including asthma.