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CFHR2 Protein, Human, Recombinant (His)
Catalog No. TMPY-03061
CFHR2 belongs to the complement factor H protein family. The human complement factor H protein family consists of the complement and immune regulators factor H, the factor H-like protein 1(FHL-1) and five factor H-related proteins (CFHR-1 to -5). Members of the H-related protein family are exclusively composed of individually folded protein domains, termed short consensus repeats (SCRs) or complement control modules. CFHR2 contains 4 Sushi (CCP/SCR) domains and is expressed by the liver and secreted in plasma. CFHR2 might be involved in complement regulation. It can associate with lipoproteins and may play a role in lipid metabolism.
CFHR2 Protein, Human, Recombinant (His)
Catalog No. TMPY-03061
CFHR2 belongs to the complement factor H protein family. The human complement factor H protein family consists of the complement and immune regulators factor H, the factor H-like protein 1(FHL-1) and five factor H-related proteins (CFHR-1 to -5). Members of the H-related protein family are exclusively composed of individually folded protein domains, termed short consensus repeats (SCRs) or complement control modules. CFHR2 contains 4 Sushi (CCP/SCR) domains and is expressed by the liver and secreted in plasma. CFHR2 might be involved in complement regulation. It can associate with lipoproteins and may play a role in lipid metabolism.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μg | $600 | 7-10 days |
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| Biological Activity | Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Description | CFHR2 belongs to the complement factor H protein family. The human complement factor H protein family consists of the complement and immune regulators factor H, the factor H-like protein 1(FHL-1) and five factor H-related proteins (CFHR-1 to -5). Members of the H-related protein family are exclusively composed of individually folded protein domains, termed short consensus repeats (SCRs) or complement control modules. CFHR2 contains 4 Sushi (CCP/SCR) domains and is expressed by the liver and secreted in plasma. CFHR2 might be involved in complement regulation. It can associate with lipoproteins and may play a role in lipid metabolism. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-His |
| Accession Number | P36980-1 |
| Synonyms | HFL3,FHR2,complement factor H-related 2,CFHL2 |
| Construction | A DNA sequence encoding the human CFHR2 (P36980-1) (Met1-Lys270) was expressed with a polyhistidine tag at the C-terminus. Predicted N terminal: Glu 19 |
| Protein Purity | > 90 % as determined by SDS-PAGE |
| Molecular Weight | 30.2 kDa (predicted); 31 and 35 kDa (reducing conditions) |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
| Reconstitution | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
| Stability & Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, Lyophilized powders are shipping with blue ice. |
| Research Background | CFHR2 belongs to the complement factor H protein family. The human complement factor H protein family consists of the complement and immune regulators factor H, the factor H-like protein 1(FHL-1) and five factor H-related proteins (CFHR-1 to -5). Members of the H-related protein family are exclusively composed of individually folded protein domains, termed short consensus repeats (SCRs) or complement control modules. CFHR2 contains 4 Sushi (CCP/SCR) domains and is expressed by the liver and secreted in plasma. CFHR2 might be involved in complement regulation. It can associate with lipoproteins and may play a role in lipid metabolism. |
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