CGB5 Protein, Human, Recombinant (mFc)

Catalog No. TMPY-01122

The human CGB5 gene encodes chorionic gonadotropin (hCG)beta 5, which is aberrantly expressed in trophoblastic neoplasm and in some non-trophoblastic neoplasms. Fucntional studies observed that it involved tumor initiation, growth, and metastatic outgrowth. Carriage of particular variants in the promoter of the CGB5 gene seems to protect against RM. CGB5 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 41.9 kDa and the accession number is A0A0F7RQP8.

CGB5 Protein, Human, Recombinant (mFc)

Catalog No. TMPY-01122

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100 μg	$700	7-10 days

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Product Information

Biological Activity	Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	The human CGB5 gene encodes chorionic gonadotropin (hCG)beta 5, which is aberrantly expressed in trophoblastic neoplasm and in some non-trophoblastic neoplasms. Fucntional studies observed that it involved tumor initiation, growth, and metastatic outgrowth. Carriage of particular variants in the promoter of the CGB5 gene seems to protect against RM. CGB5 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 41.9 kDa and the accession number is A0A0F7RQP8.
Species	Human
Expression System	HEK293 Cells
Tag	C-mFc
Accession Number	P0DN86
Synonyms	hCGB,HCG,chorionic gonadotropin β subunit 5,chorionic gonadotropin beta subunit 5,CGB5,CGB
Construction	A DNA sequence encoding the human CGB5 (NP_000728.1) (Met1-Gln165) was expressed with the Fc region of mouse IgG1 at the C-terminus. Predicted N terminal: Ser 21
Protein Purity	> 90 % as determined by SDS-PAGE
Molecular Weight	41.9 kDa (predicted); 56 kDa (reducing conditions)
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, Lyophilized powders are shipping with blue ice.
Research Background	The human CGB5 gene encodes chorionic gonadotropin (hCG)beta 5, which is aberrantly expressed in trophoblastic neoplasm and in some non-trophoblastic neoplasms. Fucntional studies observed that it involved tumor initiation, growth, and metastatic outgrowth. Carriage of particular variants in the promoter of the CGB5 gene seems to protect against RM.