Claudin-3 Protein-VLP, Human, Recombinant (His)

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Claudin-3 Protein-VLP, Human, Recombinant (His)

Catalog No. TMPH-01103

Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Claudin-3 Protein-VLP, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-10xHis tag. The predicted molecular weight is 24.7 kDa and the accession number is O15551.

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Pack Size	Price	Availability
20 μg	$815	20 days
100 μg	$1,790	20 days
1 mg	$9,870	20 days

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Biological Description

Biological Information	Measured by its binding ability in a functional ELISA. Immobilized Human CLDN3 at 10 μg/mL can bind Anti-CLDN3 recombinant antibody， the EC50 is 23.62-34.37 ng/mL.VLPs is negative control.
Description	Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Claudin-3 Protein-VLP, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-10xHis tag. The predicted molecular weight is 24.7 kDa and the accession number is O15551.
Species	Human
Expression System	HEK293 Cells
Tag	C-10xHis (This tag can be tested only under denaturing conditions)
Accession Number	O15551
Synonyms	Clostridium perfringens enterotoxin receptor 2,C7orf1,hRVP1,CPETR2,Claudin-3,CPE-receptor 2,CLDN3,Rat ventral prostate.1 protein homolog,CPE-R 2
Amino Acid	MSMGLEITGTALAVLGWLGTIVCCALPMWRVSAFIGSNIITSQNIWEGLWMNCVVQSTGQMQCKVYDSLLALPQDLQAARALIVVAILLAAFGLLVALVGAQCTNCVQDDTAKAKITIVAGVLFLLAALLTLVPVSWSANTIIRDFYNPVVPEAQKREMGAGLYVGWAAAALQLLGGALLCCSCPPREKKYTATKVVYSAPRSTGPGASLGTGYDRKDYV
Construction	1-220 aa
Molecular Weight	24.7 kDa (predicted)
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, 6% Trehalose, pH 7.4
Reconstitution	Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
Research Background	Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.

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