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Creatine kinase B/CKB Protein, Human, Recombinant

Catalog No. TMPY-07200

Creatine kinase B/CKB Protein, Human, Recombinant is expressed in E. coli.

Creatine kinase B/CKB Protein, Human, Recombinant

Creatine kinase B/CKB Protein, Human, Recombinant

Catalog No. TMPY-07200
Creatine kinase B/CKB Protein, Human, Recombinant is expressed in E. coli.
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Product Information

Biological Activity
Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
Creatine kinase B/CKB Protein, Human, Recombinant is expressed in E. coli.
Species
Human
Expression System
E. coli
Synonyms
HEL-S-29,HEL-211,CPK-B,CKBB,B-CK,BCK
Protein Purity
≥ 90% as determined by SDS-PAGE.
Molecular Weight43.6 kDa. (predicted)
EndotoxinPlease contact us for more information.
FormulationSupplied as sterile 20 mM Tris, 50mM NaCl, 1mM EDTA, 5mM β-ME, 50% Glycerol, pH 7.4. Please contact us for any concerns or special requirements. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability & Storage
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
Research Background
CKB(Creatine kinase B type) contains 1 phosphagen kinase C-terminal domain and 1 phosphagen kinase N-terminal domain. It belongs to the ATP:guanido phosphotransferase family. CKB consists of a homodimer of two identical brain-type CK-B subunits. CKB is a cytoplasmic enzyme involved in cellular energy homeostasis, with certain fractions of the enzyme being bound to cell membranes, ATPases, and a variety of ATP-requiring enzymes in the cell. There, CKB forms tightly coupled microcompartments for in situ regeneration of ATP that has been used up. CKB reversibly catalyzes the transfer of "energy-rich" phosphate between ATP and creatine or between phospho-creatine (PCr) and ADP. Its functional entity is a homodimer in brain, smooth muscle as well as in other tissues and cells such as neuronal cells, retina, kidney, bone etc.

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Please read the User Guide of Recombinant Proteins for more specific information.