Immobilized CXCR3 Protein-VLP, Human, Recombinant (Flag & His-Strep) (Cat#TMPY-07103) at 5 μg/mL (100 μL/well) can bind Anti-CXCR3 Monoclonal Antibody, Human IgG1, the EC50 is 6-20 ng/mL.

CXCR3 Protein-VLP, Human, Recombinant (Flag & His-Strep) is expressed in HEK293 Cells. The accession number is P49682.

Human

HEK293 Cells

Mig-R,MigR,IP10-R,GPR9,CMKAR3,CKR-L2,CD183,CD182

A DNA sequence encoding the Human CXCR3 (P49682) (Met1-Leu368) was expressed, with a Flag tag at the N-terminus, a polyhistidine tag and a strep tag at the C-terminus.

Samples are stable for up to twelve months from date of receipt at -70℃. Store it under sterile conditions at -70℃ or lower. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

The chemokine receptor CXCR3 plays an important role in T cell recruitment in various immune responses and autoimmune diseases. CXCR3 overexpression in GC is associated with increased DC and TIL infiltration and improved OS, and thus could be further exploited as a biomarker of favorable prognosis and a therapeutic target in GC. CXCR3 is a chemokine receptor expressed on a wide range of leukocytes, and it is involved in leukocyte migration throughout the blood and lymphatics.