Immobilized CXCR6 Protein-VLP, Human, Recombinant (Flag & His-Strep) (Cat#TMPY-07101) at 5 μg/mL (100 μL/well) can bind Anti-CXCR6 Monoclonal Antibody, Human IgG1, the EC50 is 1-5 ng/mL.

CXCR6 Protein-VLP, Human, Recombinant (Flag & His-Strep) is expressed in HEK293 Cells. The accession number is O00574.

CXCR6, the receptor for CXCL16, is expressed on multiple cell types and can be a coreceptor for human immunodeficiency virus 1. Chemokine (C-X-C motif) receptor 6 (CXCR6) is up-regulated in many malignancies, indicating that CXCR6 plays an important role in tumor progression. CXCR6 enhances OS cell proliferation and invasion through the Akt pathway. The CXC-chemokine receptor 6 (CXCR6) is a class A GTP-binding protein-coupled receptor (GPCRs) that mediates adhesion of leukocytes by interacting with the transmembrane cell surface-expressed chemokine ligand 16 (CXCL16), and also regulates leukocyte migration by interacting with the soluble shed variant of CXCL16.