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FcRH5/FcRL5 Protein, Human, Recombinant (His & Avi), Biotinylated

Catalog No. TMPK-01145

FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE), a potent anti-mitotic agent. FcRH5/FcRL5 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 94.19 kDa and the accession number is Q96RD9-1.

FcRH5/FcRL5 Protein, Human, Recombinant (His & Avi), Biotinylated

FcRH5/FcRL5 Protein, Human, Recombinant (His & Avi), Biotinylated

Catalog No. TMPK-01145
FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE), a potent anti-mitotic agent. FcRH5/FcRL5 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 94.19 kDa and the accession number is Q96RD9-1.
Pack SizePriceAvailabilityQuantity
100 μg$1,0507-10 days
500 μg$4,2007-10 days
1 mg$6,9907-10 days
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Product Information

Biological Activity
Immobilized Anti-FcRH5 Antibody at 2μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Human FcRH5, His Tag with the EC50 of 72.0ng/ml determined by ELISA.
Description
FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE), a potent anti-mitotic agent. FcRH5/FcRL5 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 94.19 kDa and the accession number is Q96RD9-1.
Species
Human
Expression System
HEK293 Cells
TagN-His-Avi
Accession NumberQ96RD9-1
Synonyms
IFGP5,FLJ00397,FLJ00333,FcR-like protein 5,FcRL5,FCRH5MGC119593,FcRH5,DKFZp667F216,DKFZp667E2019,CD307e,CD307,BXMAS1MGC119592,BXMAS1
Construction
Gln16-Gly851
Protein Purity
> 95% as determined by Tris-Bis PAGE
Molecular Weight94.19 kDa (predicted). Due to glycosylation, the protein migrates to 90-130 kDa based on Tris-Bis PAGE result.
Endotoxin< 1 EU/μg by the LAL method.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
Reconstitution
Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & Storage
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, Lyophilized powders are shipping with blue ice.
Research Background
FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE), a potent anti-mitotic agent.

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