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FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE), a potent anti-mitotic agent. FcRH5/FcRL5 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 94.19 kDa and the accession number is Q96RD9-1.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μg | $1,050 | 7-10 days | |
500 μg | $4,200 | 7-10 days | |
1 mg | $6,990 | 7-10 days |
Biological Activity | Immobilized Anti-FcRH5 Antibody at 2μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Human FcRH5, His Tag with the EC50 of 72.0ng/ml determined by ELISA. |
Description | FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE), a potent anti-mitotic agent. FcRH5/FcRL5 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 94.19 kDa and the accession number is Q96RD9-1. |
Species | Human |
Expression System | HEK293 Cells |
Tag | N-His-Avi |
Accession Number | Q96RD9-1 |
Synonyms | IFGP5,FLJ00397,FLJ00333,FcR-like protein 5,FcRL5,FCRH5MGC119593,FcRH5,DKFZp667F216,DKFZp667E2019,CD307e,CD307,BXMAS1MGC119592,BXMAS1 |
Construction | Gln16-Gly851 |
Protein Purity | > 95% as determined by Tris-Bis PAGE |
Molecular Weight | 94.19 kDa (predicted). Due to glycosylation, the protein migrates to 90-130 kDa based on Tris-Bis PAGE result. |
Endotoxin | < 1 EU/μg by the LAL method. |
Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization. |
Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
Stability & Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
Shipping | In general, Lyophilized powders are shipping with blue ice. |
Research Background | FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE), a potent anti-mitotic agent. |
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