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Galectin-3 (Gal-3) is a 30 kDa β-galactose, highly conserved and widely distributed intracellularly and extracellularly. Gal-3 has been demonstrated in recent years to be a novel inflammatory factor participating in the process of intravascular inflammation, lipid endocytosis, macrophage activation, cellular proliferation, monocyte chemotaxis, and cell adhesion.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μg | $269 | In Stock | |
500 μg | $1,070 | 7-10 days | |
1 mg | $2,800 | 7-10 days |
Biological Activity | Mouse Galectin-3, His Tag immobilized on CM5 Chip can bind Mouse LGALS3BP, His Tag with an affinity constant of 17.56 nM as determined in SPR assay. |
Description | Galectin-3 (Gal-3) is a 30 kDa β-galactose, highly conserved and widely distributed intracellularly and extracellularly. Gal-3 has been demonstrated in recent years to be a novel inflammatory factor participating in the process of intravascular inflammation, lipid endocytosis, macrophage activation, cellular proliferation, monocyte chemotaxis, and cell adhesion. |
Species | Mouse |
Expression System | HEK293 Cells |
Tag | C-His |
Accession Number | P16110 |
Synonyms | MAC2GAL3,Mac-2,LGALS3,LGALS2,Lectin L-29,L31,L29,GALIG,Galectin3,GALBPCBP35,galactin-3,Gal-3,GAL3,CBP35,AGE-R3 |
Construction | Ala2-Ile264 |
Protein Purity | > 95% as determined by Tris-Bis PAGE |
Molecular Weight | 28.5 kDa (predicted). Due to glycosylation, the protein migrates to 43-50 kDa based on Tris-Bis PAGE result. |
Endotoxin | < 1 EU/μg by the LAL method. |
Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, 300 mM L-arginine (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization. |
Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
Stability & Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
Shipping | In general, Lyophilized powders are shipping with blue ice. |
Research Background | Galectin-3 (Gal-3) is a 30 kDa β-galactose, highly conserved and widely distributed intracellularly and extracellularly. Gal-3 has been demonstrated in recent years to be a novel inflammatory factor participating in the process of intravascular inflammation, lipid endocytosis, macrophage activation, cellular proliferation, monocyte chemotaxis, and cell adhesion. |
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