Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

GFAP Protein, Human, Recombinant (aa 1-432, His)

Catalog No. TMPY-07095

GFAP Protein, Human, Recombinant (aa 1-432, His) is expressed in E. coli. The accession number is P14136.

GFAP Protein, Human, Recombinant (aa 1-432, His)

GFAP Protein, Human, Recombinant (aa 1-432, His)

Catalog No. TMPY-07095
GFAP Protein, Human, Recombinant (aa 1-432, His) is expressed in E. coli. The accession number is P14136.
Pack SizePriceAvailabilityQuantity
100 μg $687Backorder
Bulk & Custom
Add to Cart
Questions
View More
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Information

Biological Activity
Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
GFAP Protein, Human, Recombinant (aa 1-432, His) is expressed in E. coli. The accession number is P14136.
Species
Human
Expression System
E. coli
TagN-His
Accession NumberP14136
Synonyms
FLJ45472,ALXDRD
Construction
A DNA sequence encoding the Human GFAP (P14136) (Met1-Met432) was expressed, with a polyhistidine tag at the N-terminus.
Protein Purity
≥ 90% as determined by SDS-PAGE.
Molecular Weight50.84 kDa (predicted)
Endotoxin< 1.0 EU per μg of the protein as determined by the LAL method
FormulationSupplied as sterile 20 mM Tris, 500 mM NaCl, 10% glycerol, 0.5 M UREA, pH 8.0. Please contact us for any concerns or special requirements. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability & Storage
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
Research Background
GFAP is a cell-specific marker which belongs to the intermediate filament family. It can distinguish astrocytes from other glial cells during development. GFAP is expressed in cells lacking fibronectin. It is a type III intermediate filaments protein which contains three domains: the head, rod and tail domains. GFAP functions in many important entral nervous system (CNS) processes, including cell communication and the functioning of the blood brain barrier. Improper GFAP regulation can cause multiple disorders. Defects in GFAP is related to Alexander disease which is a rare disorder of the central nervous system. It is a progressive leukoencephalopathy whose hallmark is the widespread accumulation of Rosenthal fibers which are cytoplasmic inclusions in astrocytes.

Dose Conversion

You can also refer to dose conversion for different animals. More

Calculator

  • Reconstitution Calculator
  • Recombinant Protein Dilution Calculator
  • Specific Activity Calculator

Tech Support

Please read the User Guide of Recombinant Proteins for more specific information.