Immobilized GLP1R Protein-VLP, Human, Recombinant (Flag & Strep) (Cat#TMPY-07121) at 5 μg/mL (100 μL/well) can bind Anti-GLP1R Monoclonal antibody, Human IgG1, the  EC50 is 1.5-4.5 ng/mL.

GLP1R Protein-VLP, Human, Recombinant (Flag & Strep) is expressed in HEK293 Cells. The accession number is P43220.

Human

HEK293 Cells

GLP-1-R,GLP-1R,GLP-1

A DNA sequence encoding the Human GLP1R-VLP (P43220) (Arg24-Ser463) was expressed, with a Flag tag at the N-terminus, and a strep tag at the C-terminus.

Samples are stable for up to twelve months from date of receipt at -70℃. Store it under sterile conditions at -70℃ or lower. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Glucagon-like peptide (GLP)-1 receptor is encoded by GLP1R. GLP1R plays a critical role in mediating the biological actions of GLP1 in mammals and fish. The neuronal GLP1Rs mediate body weight and anorectic effects of liraglutide, but are not required for glucose-lowering effects. Glucagon-like peptide 1 receptor (GLP1R) signaling has been shown to have antipsychotic properties in animal models and to impact glucose-dependent insulin release, satiety, memory, and learning in man. Glucagon-like peptide-1 receptor (GLP1R) and glucose-dependent insulinotropic peptide receptor (GIPR) are their indirect drug targets.