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GLP1R Protein-VLP, Human, Recombinant (Flag & Strep) is expressed in HEK293 Cells. The accession number is P43220.
Pack Size | Price | Availability | Quantity |
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Biological Activity | Immobilized GLP1R Protein-VLP, Human, Recombinant (Flag & Strep) (Cat#TMPY-07121) at 5 μg/mL (100 μL/well) can bind Anti-GLP1R Monoclonal antibody, Human IgG1, the EC50 is 1.5-4.5 ng/mL. |
Description | GLP1R Protein-VLP, Human, Recombinant (Flag & Strep) is expressed in HEK293 Cells. The accession number is P43220. |
Molecular Weight | 56.04 kDa (predicted) |
Research Background | Glucagon-like peptide (GLP)-1 receptor is encoded by GLP1R. GLP1R plays a critical role in mediating the biological actions of GLP1 in mammals and fish. The neuronal GLP1Rs mediate body weight and anorectic effects of liraglutide, but are not required for glucose-lowering effects. Glucagon-like peptide 1 receptor (GLP1R) signaling has been shown to have antipsychotic properties in animal models and to impact glucose-dependent insulin release, satiety, memory, and learning in man. Glucagon-like peptide-1 receptor (GLP1R) and glucose-dependent insulinotropic peptide receptor (GIPR) are their indirect drug targets. |
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