Shopping Cart

Remove All

Your shopping cart is currently empty

IL-11 Protein, Human, Recombinant

Resource Download

COA

IL-11 Protein, Human, Recombinant

Catalog No. TMPY-03488

IL-11 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 19.1 kDa and the accession number is AAH12506.1.

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Pack Size	Price	Availability
5 μg	$106	In Stock
10 μg	$148	7-10 days
20 μg	$206	7-10 days
50 μg	$320	7-10 days
100 μg	$447	7-10 days
200 μg	$791	7-10 days
500 μg	$1,670	7-10 days

Bulk & Custom

Add to Cart

Questions

Biological Description

Biological Information	1.Measured in a cell proliferation assay using T1165 mouse plasmacytoma cells. The ED50 for this effect is typically 1-8 ng/mL. 2.Loaded Human IL11RA Protein, His Tag on His1K Biosensor, can bind Human IL11 protein with an affinity constant of 0.353nM as determined in BLI assay (Routinely tested).
Description	IL-11 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 19.1 kDa and the accession number is AAH12506.1.
Species	Human
Expression System	E. coli
Tag	Tag Free
Accession Number	AAH12506.1
Synonyms	interleukin 11,IL-11,AGIF
Construction	mature form of Human IL11 (AAH12506.1) (Pro22-Leu199)
Protein Purity	> 90 % as determined by SDS-PAGE
Molecular Weight	19.1 kDa (predicted)
Endotoxin	Please contact us for more information.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, Lyophilized powders are shipping with blue ice.
Research Background	IL11 is a multifunctional cytokine first isolated in 199 from bone marrow-derived stromal cells. It is a key regulator of multiple events in hematopoiesis, most notably the stimulation of megakaryocyte maturation. IL11 is also known under the names adipogenesis inhibitory factor (AGIF) and oprelvekin. IL11 can improve platelet recovery after chemotherapy-induced thrombocytopenia, induce acute-phase proteins, modulate antigen-antibody responses, participate in the regulation of bone cell proliferation and differentiation, and could be used as a therapeutic for osteoporosis. IL11 stimulates the growth of certain lymphocytes and, in the murine model, stimulates an increase in the cortical thickness and strength of long bones. As a signaling molecule, IL11 has a variety of functions associated with its receptor interleukin 11 receptor alpha; such functions include placentation and to some extent of decidualization.