IL-22 Protein, Mouse, Recombinant (His & Avi), Biotinylated

Catalog No. TMPK-01194

The cytokine interleukin-22 (IL-22) is a critical regulator of epithelial homeostasis. It has been implicated in multiple aspects of epithelial barrier function, including regulation of epithelial cell growth and permeability, production of mucus and antimicrobial proteins (AMPs), and complement production. IL-22 Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in E. coli expression system with N-His-Avi tag. The predicted molecular weight is 19.7 kDa and the accession number is Q9JJY9.

IL-22 Protein, Mouse, Recombinant (His & Avi), Biotinylated

Catalog No. TMPK-01194

Pack Size	Price	Availability
100 μg	$814	7-10 days
500 μg	$3,250	7-10 days
1 mg	$5,440	7-10 days

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Product Information

Biological Activity	1. Immobilized Biotinylated Mouse IL-22, His Tag at 2μg/ml (100μl/well) on the streptavidin precoated plate (5μg/ml). Dose response curve for Mouse IL-22R alpha 1, hFc Tag with the EC50 of 6.2ng/ml determined by ELISA. 2. Rat IL-22R alpha 1, His Tag immobilized on CM5 Chip can bind Biotinylated Mouse IL-22, His Tag with an affinity constant of 0.145 μM as determined in SPR assay.
Description	The cytokine interleukin-22 (IL-22) is a critical regulator of epithelial homeostasis. It has been implicated in multiple aspects of epithelial barrier function, including regulation of epithelial cell growth and permeability, production of mucus and antimicrobial proteins (AMPs), and complement production. IL-22 Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in E. coli expression system with N-His-Avi tag. The predicted molecular weight is 19.7 kDa and the accession number is Q9JJY9.
Species	Mouse
Expression System	E. coli
Tag	N-His-Avi
Accession Number	Q9JJY9
Synonyms	ZCYTO18,TIFIL-23,TIFa,Interleukin-22,IL-TIF,IL-D110,IL-22,Cytokine Zcyto18
Construction	Leu34-Val179
Protein Purity	> 95% as determined by Tris-Bis PAGE; > 90% as determined by HPLC
Molecular Weight	19.7 kDa (predicted) same as Tris-Bis PAGE result.
Endotoxin	< 1 EU/μg by the LAL method.
Formulation	Supplied as 0.22 μm filtered solution in 50 mM Na2CO3/NaHCO3, 500 mM NaCl (pH 10.0).
Stability & Storage	It is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	Shipping with blue ice.
Research Background	The cytokine interleukin-22 (IL-22) is a critical regulator of epithelial homeostasis. It has been implicated in multiple aspects of epithelial barrier function, including regulation of epithelial cell growth and permeability, production of mucus and antimicrobial proteins (AMPs), and complement production.